Study Shows Dramatic Drop in Blood Culture Contamination Rates Through Novel Device, Training

Contact: Heather Woolwine
843-792-7669
woolwinh@musc.edu

Jan. 24, 2018

CHARLESTON, SC – A Medical University of South Carolina (MUSC Health) research study found that use of a mechanical initial specimen diversion device (ISDD) and staff education led to a nearly four-fold decrease in contaminated blood cultures that was sustained over 20 months.

Results of the emergency department research were presented recently at the Institute for Health care Improvement National Forum by lead study author Lisa Steed, Ph.D., MUSC Department of Pathology and Laboratory Medicine professor.

“Working on this study and seeing such strong results speaks to the great things that can happen for patients when clinicians join forces on these issues,” Steed said. “Blood cultures, and the accuracy of those cultures, are incredibly important in making sure that patients are getting the right care, at the right time, and with the right process in place.”

Blood cultures help physicians determine whether patients have serious and potentially life-threatening blood infections such as sepsis. These blood draws may become contaminated with bacteria-containing fragments of a patient’s skin that enter the needle during the blood collection process. Studies have shown that conventional techniques can lead to false positives which in turn may lead to patients receiving more blood draws, extended length of stay, increased exposure to hospital-acquired conditions, and unnecessary antibiotic treatment.

The mechanical ISDD used in the study, called Steripath, is a sterile, closed blood culture collection system that diverts, sequesters, and isolates the first 1.5 to 2 milliliters of blood – the portion that is known to contain contaminants – during the blood draw.

“We’ve seen a significant reduction of blood culture contaminations in our emergency department by using this device, along with education and training,” said Danielle Scheurer, M.D., MUSC Health chief quality officer. “By lessening the chances of contaminating a specimen, we increase our accurate diagnoses and treat patients with real infections. This in turn leads to decreased antibiotic use and allows us to help mitigate the ongoing, nationwide problem of antibiotic resistance from over or improper use.” 

The study also showed that use of the mechanical ISDD could reduce costs and use staff time more efficiently. Researchers suggested that MUSC would have saved $744,955 if the ISDD had been used for every blood draw in the emergency department during the study, based on a conservative estimate ($4,850) for the cost of a contaminated culture.

The Institute of Health care Improvement National Forum was held December 11, 2017 in Orlando, Florida.
This study was funded by MUSC Health and does not constitute a product endorsement.

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Founded in 1824 in Charleston, MUSC is the state's only comprehensive academic health system, with a unique mission to preserve and optimize human life in South Carolina through education, research and patient care. Each year, MUSC educates more than 3,200 students in six colleges – Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing, and Pharmacy – and trains more than 900 residents and fellows in its health system. MUSC brought in more than $300 million in research funds in fiscal year 2023, leading the state overall in research funding. MUSC also leads the state in federal and National Institutes of Health funding. Learn more about our academic programs.

As the health care system of the Medical University of South Carolina, MUSC Health is dedicated to delivering the highest-quality and safest patient care while educating and training generations of outstanding health care providers and leaders to serve the people of South Carolina and beyond. Patient care is provided at 16 hospitals (includes owned or governing interest), with approximately 2,700 beds and four additional hospital locations in development, more than 350 telehealth sites and nearly 750 care locations situated in all regions of South Carolina. In 2023, for the ninth consecutive year, U.S. News & World Report named MUSC Health University Medical Center in Charleston the Number 1 hospital in South Carolina. Learn more about our patient services.

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